hrp0092p1-75 | GH and IGFs | ESPE2019

Impact of -202 IGFBP-3 Promoter Polymorphism on Growth Responses in Korean Children with Idiopathic Short Stature

Hwang II Tae , Yi Kyung Hee , Kim Eun Young , Yang Seung

Purpose: Our previous study showed no correlation between -202 A/C IGFBP-3 promoter polymorphism and Δheight SDS in children with growth hormone deficiency. We investigated the influences of the -202 IGFBP-3 polymorphism on 1-year follow-up outcomes of GH treatment in Korean children with ISS.Methods: Data was obtained from 81 children with idiopathic short stature (peak serum growth hormone (GH) ≥ 7.0 ng/mL b...